3小结与讨论
本试验对南海红树林内生真菌ZH-7代谢产物进行研究,从培养液中分离得到6个化合物:比卡菌素(1),butyrolactoneⅡ(2),环(苯丙-脯)二肽(3),环(苯丙-苯丙)二肽(4),环(苯丙-缬)二肽(5),环(苯丙-亮)二肽(6)。初步药理活性显示化合物1对口腔癌细胞KB,KBv200抗肿瘤活性的IC50值分别为10.0和14.5μg/mL。
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